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Home > Process Development > Optimization and Scale-up
Optimization and Scale-up
Optimization and Scale-up Optimization and Scale-up

Optimization and Scale-up

Optimization delivers a process which is appropriately fit-for-purpose.

Examples of Targets include.

  • -Maximizing overall yields

  • -Minimizing solvent volumes

  • -Substitution of high-cost materials/reagents

  • -Simplification of work-up and isolation procedures

  • -Robustness and failure boundary determination

  • -Impurity level controls

Scale-dependance studies are conducted to reveal the parameters controls required. Scale-up demonstration batches are carried out to affirm or challenge the scale-dependance understanding and prepare a process for manufacturing.